Products
MICAL1 antibody
- Product Name
- MICAL1 antibody
- Catalogue No.
- FNab05177
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- microtubule associated monoxygenase, calponin and LIM domain containing 1
- Alternative Names
- MICAL antibody, MICAL 1 antibody, MICAL1 antibody, NICAL antibody
- UniProt ID
- Q8TDZ2
- Observed MW
- 120 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP, FC
- Recommended dilution
- WB: 1:1000-1:4000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05177(MICAL1 antibody) at dilution of 1:1000
IP result of anti-MICAL1(IP: FNab05177, 5ug; Detection: FNab05177 1:1000) with Hela cells lysate 2000 ug
Immunohistochemistry of paraffin-embedded human lung using FNab05177(MICAL1 antibody) at dilution of 1:100
Immunofluorescent analysis of ( -20°C Ethanol) fixed HeLa cells using FNab05177 (MICAL1 antibody) at dilution of 1:50 and Alexa Fluor 488-Conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization(Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4.
